Genetic Code

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Genetic Code: Overview

This Topic covers sub-topics such as Genetic Code, Wobble Hypothesis and, Characteristics of Genetic Code

Important Questions on Genetic Code

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Which of the following is not a salient feature of genetic code?

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Which of the following codon perform dual function?

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Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?

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During protein synthesis in an organism, at one point the process comes to a halt. Select the group of the three codons from the following, from which anyone of the three could bring about this halt.

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Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?

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Which one of the following codons codes for the same information as UGC?

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Identify the correct statement from the following:

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Khorana performed experiments to decipher the codons that code for a particular amino acid. The results of these experiments using synthetic mRNAs and the corresponding polypeptide repeats that were generated are given in the table below.

Synthetic mRNAs Polypeptide(s) synthesized
CAAn Thr-Thrn and Asn-Asnn and Gln-Glnn
UUCn Ser-Sern and Leu-Leun and Phe-Phen
UACn Thr-Thrn and Leu-Leun and Tyr-Tyrn
UUACn Leu-Leu-Thr-Tyrn

Based on the results, the correct combination(s) of codons and amino acids is/are

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Which of the following statements correctly describes a codon?

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How many nucleotides of DNA are required to code a polypeptide if in an E.coli, a finished polypeptide has 162 amino acids of which the first amino acid is not a methionine compound?

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GUG normally codes for valine, but at start position, it codes for methionine. The given statement is an exception to which property of genetic code?

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The amino acid serine (Ser) is coded by four codons. What does this show?

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State the number of amino acids produced by the given mRNA sequence when the 16th base is substituted by uracil.

5' A U G C G C A A A C C C U A G C G A 3'

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Which of the following codons acts as initiator codon and codes for methionine also?

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If the genetic code is tetraplet, then what is the possible number of codons which code 20 amino acids?

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The number of codons that code different amino acids is

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What would be the result if a gene encoding a polypeptide of 50 amino acids undergoes nonsense mutation at the 25th codon, i.e., UAC into UAA?

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The genetic code translates the language of

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Of the __A__ different possible codons, __B__ specify amino acids and __C__ codons do not specify any amino acids.

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How many of the following statements are correct with respect to genetic code?

(i) The codon is read in mRNA in a contiguous fashion.

(ii) One codon does not overlap the next codon.

(iii) The code is nearly universal.

(iv) Ochre, amber and opal are terminator codons.

(v) Only tryptophan and methionine are specified by a single codon.